Drug Trial One PTSD Drug Trials

NYU – Pfizer Drug Trial: Day 1 Triggering Sessions Begin

Day One is DONE
Day One is DONE

(Original post on Facebook blog can be viewed by clicking here)

Pfizer Drug Trial: Day 1 (Visit 2)
….is done. It was a long day, but productive. It’s hard to tell if the meds worked (or if I received actual medication at all – it could be a placebo) because of being in a stressful situation – fMRI scans, mild electrical shocks to the wrist to induce stress, etc. – but the worst is over. Tomorrow I only have one fMRI/trigger session, then I’ll be able to get a better idea of how the meds affect me because I’ll be in a more normal environment.

Today’s happenings: after reporting to the NYU School of Medicine Clinical and Translational Science Institute (CTSI), an IV was placed, ECG completed, and several blood tests were taken. Various assessments were given, and the obligatory drug and pregnancy screenings were completed, as well as a breathalyzer to verify that I hadn’t consumed any alchohol. We were good to go, so on to the next phase.

I was transported to the Center for Biomedical Imaging (CBI) for my first fMRI. Electrodes were placed on my body to measure any muscle movements, and an elastic belt was placed around my abdomen to measure the depth of my breathing during the scan. An electrode was also placed on my finger to measure my oxygen levels.

Electrodes were attached to my palms to see how much I was sweating, and a special video camera recorded my eye movements and blinking.

After testing increasing shock levels to determine the maximum that I could tolerate without it being painful, I was slid into the imaging machine and the scan began.

I received electric shocks to the inside of my wrists as a trigger, along with being shown images of people with different expressions of disgust, anger, etc. on a video screen. I was also shown images of different shapes and colors, and told to predict whether or not I would receive a shock by pushing buttons on a small handheld device.

After about an hour I was allowed to rest for ten minutes while they completed the fMRI scan of my brain.

IT SUCKED.

I then went back to CTSI to take my first dose, and then was monitored for a few hours. Later that afternoon, I was again transported to CBI for another fMRI and triggering session.

IT ALSO SUCKED.

Oh my god. That was a really long fucking day.

Right now I’m working on getting rid of a massive headache, hopefully caused by the lack of caffeine and not the trial med. Another hope? That I came out on the right side of the coin toss and am getting the actual meds and not a placebo. Only time will tell. Once again, the staff at NYU have proven themselves to be exceptional. I couldn’t be in better hands.

The one thing I would change is getting a ride back to my hotel. I’ve been responsible for my own transportation, so it did feel kind of weird to be just turned loose outside the building to find my own way home, especially so late at night. It was a VERY LONG, ten hour day today, so I am *exhausted* both physically and mentally. My headache is so bad that I decided I just couldn’t wait on a cab and so I walked the two blocks back to the hotel.

Did I mention that I was exhausted?

On another note – check out the luggage under my eyes! Those are some serious bags!

Enough complaining. I’m so lucky to be here!! Even though I feel like pounded shit, I have never felt so HOPEFUL.

Onward. 🙂

 

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44 comments

Annie Lendshishorse Phillips January 22, 2015 at 6:42 pm

<3

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Diane January 22, 2018 at 6:48 pm

<3 to you as well

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Nancy Guerra Tubbs January 22, 2015 at 6:47 pm

Yaye!! So brave!!!

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Diane January 22, 2015 at 6:52 pm

Thanks Nancy…I’m not sure if it’s so much bravery as it is determination 🙂

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Nancy Guerra Tubbs January 22, 2018 at 7:29 pm

Either way girl, you got both! Very proud.

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Heather McAllister January 22, 2015 at 6:50 pm

you are one of the most beautiful and inspirational people I’ve ever come across. take care and safe travels.

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Diane January 22, 2015 at 6:57 pm

Thank you so much… you gave me a smile 🙂

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Sonja Sunny Frederic January 22, 2015 at 6:55 pm

Ahh you’re a redhead!! So is my daughter!! You’re a beauty, especially your spirit!!

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Diane January 22, 2015 at 7:30 pm

Redheads unite! 😀 Thanks for the well wishes <3

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January Lynn Carpenter January 22, 2015 at 6:56 pm

Glad the worst is over and hope tomorrow goes well!

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Diane January 22, 2015 at 7:16 pm

So far, so good!

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Rhonda Greenfield Lanclos January 22, 2015 at 6:58 pm

Get well soon!

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Diane January 22, 2015 at 7:20 pm

Thanks Rhonda 🙂

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Lisa McGuire January 22, 2015 at 7:06 pm

Still gorgeous x

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Diane January 22, 2015 at 7:22 pm

Thanks Lisa…I hope we get to see each other again soon! Viva Las Vegas 😉

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Lisa McGuire January 22, 2015 at 7:34 pm

If there is the slightest chance you and Robert can be in Vegas in March I would love love love to see you x

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Gina Bailey Plath January 22, 2015 at 7:10 pm

You are beautiful inside and out. Never forget that.

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Diane January 22, 2015 at 7:19 pm

Thank you! <3

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Martin Priest January 22, 2015 at 7:13 pm

Good luck hope all goes well

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Diane January 22, 2015 at 7:20 pm

Thank you 🙂

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Martin Priest January 22, 2015 at 7:22 pm

You are very welcome don’t worry about the bags under eyes you are a very pretty lady. Again good luck

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Diane January 22, 2015 at 7:23 pm

Hehe…the bags under my eyes are the least of my worries

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Martin Priest January 22, 2015 at 7:29 pm

Well I do hope it gets better. Love your post

Donna Marie Mchugh January 22, 2015 at 7:15 pm

God bless you baby

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Diane January 22, 2015 at 7:21 pm

Thank you <3

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KT Froggle January 22, 2015 at 7:16 pm

<3 good luck with it all. Hope the headache subsides asap.

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Diane January 22, 2015 at 7:41 pm

Thank you, it’s starting to ease up a little so I’m thinking it was the lack of caffeine (I was prohibited from caffeine intake until after the scans were finished for the day). I’m going to call it a night and get some rest. 🙂

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Martha Reed January 22, 2015 at 7:18 pm

sweet blessings to you!

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Diane January 22, 2015 at 7:24 pm

Thank you Martha <3

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Jessica Trevino January 22, 2015 at 7:20 pm

*hugs* we’re all with you in spirit!

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Diane January 22, 2015 at 7:24 pm

And I certainly can feel it. Thank you! <3

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Debbie Neese January 22, 2015 at 7:21 pm

You look marvelous to have went through so much .
I so pray , this helps and gives you your health and life a boast ..
Such a pretty young lady .. So proud of you and your journey ..
Thank you all at NYU ..!!

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Diane January 22, 2015 at 7:32 pm

Thank you <3 Words of support really do help

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Bethany Miller January 22, 2015 at 7:26 pm

Doing great.. Stay positive

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Diane January 22, 2015 at 7:40 pm

Thank you 🙂

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Desiree Fires January 22, 2015 at 7:26 pm

Doing great cous. So glad you have this opportunity, I hope it helps you! Stay strong and get some sleep. Love ya!

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Diane January 22, 2015 at 7:42 pm

Thank you, love you too! <3

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Lisa Knox Prevost January 22, 2015 at 7:29 pm

Gorgeous and mysterious; many thoughts and prayers for you! You have been such an inspiration to me!

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Diane January 22, 2015 at 7:46 pm

Thank you for being so sweet 🙂

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Lisa Knox Prevost January 22, 2015 at 7:55 pm

I have a daughter who is a brain aneurysm survivor. She faces new challenges everyday and suffers from depression. I use a lot of your post to help her because they have helped me overcome so many skeletons in my closet! Sending you hugs!

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Diane January 22, 2015 at 8:12 pm

Thank you! Sending positive thoughts and much love to both you and your daughter <3

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The evolution of mi January 22, 2015 at 8:42 pm

You look fabulous!! You are a warrior, don’t forget that. Feel better soon!

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Karen DeMello January 22, 2015 at 9:33 pm

You look good. Every day will be better and easier than the one before. And yes, lack of caffeine is probably the cause of the headache. Onward and upward!

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Diane January 22, 2015 at 9:46 pm

That’s right…onward and upward 🙂 I gulped down some coffee, here’s hoping it works and soon.

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