ptsd science

Why can’t you just get over it? There could be a biological reason.

This question, while highly offensive when asked in the usual manner, deserves an answer. Those of us who suffer from PTSD day after day and year after year – WE deserve answers.And now we are getting them. Do you feel jumpy all the time? Find it impossible to get to sleep? Have recurring nightmares? Are you angry or irritable for no apparent reason? There’s a reason for that, and it has nothing to do with character flaws. Below you’ll see brain scans of three different people: – one who experienced trauma and developed PTSD (PTSD) – one who experienced trauma

Allostatic Load and Stress-Related Disease

Allostatic load (AL) is a term used to describe the cumulative physiological wear and tear that results from repeated efforts to adapt to stressors over time. Unlike other psychobiological models of stress that focus on a single outcome variable (e.g., cortisol) or physiological system (e.g., the hypothalamic-pituitary-adrenal –HPA- axis), the AL model emphasizes multi-system dysregulation. By combining multiple biological risk factors into a composite score, risk for a variety of stress-exacerbated diseases can be assessed in healthy individuals prior to signs and symptoms of clinical disease. Also, use of a composite AL may allow for quantification of stress burden across